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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EP300
All Species:
20.61
Human Site:
S545
Identified Species:
37.78
UniProt:
Q09472
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q09472
NP_001420.2
2414
264161
S545
N
S
Q
N
P
M
M
S
E
N
A
S
V
P
S
Chimpanzee
Pan troglodytes
XP_515155
2411
263753
S545
N
S
Q
N
P
M
M
S
E
N
A
S
V
P
S
Rhesus Macaque
Macaca mulatta
XP_001102844
2414
264251
S545
N
S
Q
N
P
M
M
S
E
N
A
S
V
P
S
Dog
Lupus familis
XP_851777
2404
260682
S528
N
P
L
M
S
D
G
S
S
P
A
N
I
G
T
Cat
Felis silvestris
Mouse
Mus musculus
P45481
2441
265456
S565
N
P
L
M
N
D
G
S
N
S
G
N
I
G
S
Rat
Rattus norvegicus
XP_001076610
2413
263563
N546
N
S
Q
N
P
M
M
N
E
N
A
S
V
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233888
2444
267496
S550
N
S
Q
N
S
M
M
S
E
S
A
N
V
A
S
Frog
Xenopus laevis
NP_001088637
2428
264402
S553
L
S
D
G
N
S
P
S
T
V
G
N
L
G
T
Zebra Danio
Brachydanio rerio
XP_001332718
2667
289125
A553
S
K
K
V
N
K
G
A
N
L
I
N
D
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524642
3276
340709
N917
N
A
G
N
P
N
Q
N
A
G
G
V
A
G
G
Honey Bee
Apis mellifera
XP_001122031
2606
284119
R698
L
S
V
P
N
E
N
R
L
A
N
L
Q
L
P
Nematode Worm
Caenorhab. elegans
P34545
2056
227161
L405
Q
D
P
E
K
R
K
L
I
Q
Q
Q
L
V
L
Sea Urchin
Strong. purpuratus
XP_782558
2635
288594
S792
S
S
F
Q
G
M
N
S
L
S
N
T
L
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.2
61
N.A.
58.6
94.1
N.A.
N.A.
85.1
60.4
57
N.A.
36.2
43
31.1
39.5
Protein Similarity:
100
99.7
99.5
72.4
N.A.
69.5
96.1
N.A.
N.A.
89.9
71
65.9
N.A.
46.6
54.9
45.6
51.5
P-Site Identity:
100
100
100
20
N.A.
20
86.6
N.A.
N.A.
73.3
13.3
0
N.A.
20
6.6
0
20
P-Site Similarity:
100
100
100
40
N.A.
40
93.3
N.A.
N.A.
86.6
33.3
26.6
N.A.
33.3
6.6
6.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
8
8
8
47
0
8
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
16
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
8
0
8
0
0
39
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
8
0
24
0
0
8
24
0
0
31
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
8
0
16
0
0
% I
% Lys:
0
8
8
0
8
8
8
0
0
0
0
0
0
0
0
% K
% Leu:
16
0
16
0
0
0
0
8
16
8
0
8
24
8
8
% L
% Met:
0
0
0
16
0
47
39
0
0
0
0
0
0
0
0
% M
% Asn:
62
0
0
47
31
8
16
16
16
31
16
39
0
0
8
% N
% Pro:
0
16
8
8
39
0
8
0
0
8
0
0
0
24
8
% P
% Gln:
8
0
39
8
0
0
8
0
0
8
8
8
8
0
0
% Q
% Arg:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% R
% Ser:
16
62
0
0
16
8
0
62
8
24
0
31
0
8
47
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
8
0
8
16
% T
% Val:
0
0
8
8
0
0
0
0
0
8
0
8
39
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _